HIV-2EU: supporting standardized HIV-2 drug resistance interpretation in Europe

Clin Infect Dis. 2013 Jun;56(11):1654-8. doi: 10.1093/cid/cit104. Epub 2013 Feb 19.

Abstract

Considering human immunodeficiency virus type 2 (HIV-2) phenotypic data and experience from HIV type 1 and from the follow-up of HIV-2-infected patients, a panel of European experts voted on a rule set for interpretation of mutations in HIV-2 protease, reverse transcriptase, and integrase and an automated tool for HIV-2 drug resistance analyses freely available on the Internet (http://www.hiv-grade.de).

Keywords: HIV-2; Internet tool; drug-resistance rules.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-HIV Agents / pharmacology
  • Consensus Development Conferences as Topic
  • Drug Resistance, Viral
  • Europe
  • HIV Infections / virology*
  • HIV Integrase / genetics
  • HIV Protease / genetics
  • HIV Reverse Transcriptase / genetics
  • HIV-2 / classification*
  • HIV-2 / drug effects
  • HIV-2 / enzymology
  • HIV-2 / genetics
  • Humans
  • Internet
  • Mutation*
  • User-Computer Interface

Substances

  • Anti-HIV Agents
  • HIV Integrase
  • reverse transcriptase, Human immunodeficiency virus 2
  • HIV Reverse Transcriptase
  • HIV Protease