A simple, rapid, low-cost diagnostic test for sickle cell disease

Xiaoxi Yang; Julie Kanter; Nathaniel Z Piety; Melody S Benton; Seth M Vignes; Sergey S Shevkoplyas

doi:10.1039/c3lc41302k

A simple, rapid, low-cost diagnostic test for sickle cell disease

Lab Chip. 2013 Apr 21;13(8):1464-7. doi: 10.1039/c3lc41302k.

Authors

Xiaoxi Yang¹, Julie Kanter, Nathaniel Z Piety, Melody S Benton, Seth M Vignes, Sergey S Shevkoplyas

Affiliation

¹ Department of Biomedical Engineering, Tulane University, New Orleans, LA 70118, USA.

PMID: 23429713
DOI: 10.1039/c3lc41302k

Abstract

This communication describes a very simple, rapid and inexpensive point-of-care diagnostic test for sickle cell disease (SCD) that can conclusively differentiate between blood samples from normal healthy individuals, sickle cell trait carriers and SCD patients using the characteristic blood stain patterns produced by each sample on paper.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anemia, Sickle Cell / blood
Anemia, Sickle Cell / diagnosis*
Colorimetry
Hemoglobin, Sickle / chemistry
Hemoglobin, Sickle / metabolism
Humans
Microfluidic Analytical Techniques / instrumentation
Microfluidic Analytical Techniques / methods
Point-of-Care Systems
Polymerization

Substances

Hemoglobin, Sickle