Neurogenesis in zebrafish - from embryo to adult

Neural Dev. 2013 Feb 21;8:3. doi: 10.1186/1749-8104-8-3.


Neurogenesis in the developing central nervous system consists of the induction and proliferation of neural progenitor cells and their subsequent differentiation into mature neurons. External as well as internal cues orchestrate neurogenesis in a precise temporal and spatial way. In the last 20 years, the zebrafish has proven to be an excellent model organism to study neurogenesis in the embryo. Recently, this vertebrate has also become a model for the investigation of adult neurogenesis and neural regeneration. Here, we summarize the contributions of zebrafish in neural development and adult neurogenesis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Differentiation / physiology
  • Central Nervous System / embryology*
  • Central Nervous System / growth & development*
  • Neural Stem Cells / cytology
  • Neurogenesis / physiology*
  • Neurons / cytology
  • Zebrafish / embryology*
  • Zebrafish / growth & development*