Initially disadvantaged, TEL-AML1 cells expand and initiate leukemia in response to irradiation and cooperating mutations

Leukemia. 2013 Jul;27(7):1570-3. doi: 10.1038/leu.2013.15. Epub 2013 Jan 16.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Core Binding Factor Alpha 2 Subunit / genetics*
  • Disease Models, Animal*
  • Green Fluorescent Proteins / genetics
  • Hematopoietic Stem Cells / drug effects*
  • Hematopoietic Stem Cells / pathology
  • Humans
  • Mice
  • Mice, Transgenic*
  • Neoplasms, Radiation-Induced / pathology*
  • Oncogene Proteins, Fusion / genetics*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology*

Substances

  • Core Binding Factor Alpha 2 Subunit
  • Oncogene Proteins, Fusion
  • TEL-AML1 fusion protein
  • enhanced green fluorescent protein
  • Green Fluorescent Proteins