Spontaneous cutaneous endometriosis in the mons pubis region: a case report diagnosed by fine-needle aspiration biopsy

Diagn Cytopathol. 2014 Jul;42(7):615-8. doi: 10.1002/dc.22961. Epub 2013 Feb 27.


Most cutaneous endometriosis develops at the site of an abdominal surgical scar. Spontaneous cutaneous endometriosis is extremely rare. We report a case of spontaneous cutaneous endometriosis in the mons pubis region. A 41-year-old woman presented with a mass in the right mons pubis, causing cyclic pain associated with menses. Fine-needle aspiration (FNA) biopsy was performed. The smears contained three cellular components: honeycombed sheets of glandular epithelial cells, fragments of ovoid-to-spindle shaped stromal cells, and background inflammatory cells, including hemosiderin-laden macrophages, histiocytes, and neutrophils. Biphasic clusters of glandular epithelial cells and stromal cells were identified. FNA cytology is a safe and useful adjunctive tool for diagnosing cutaneous endometriosis.

Keywords: endometriosis; fine-needle aspiration; mons pubis.

MeSH terms

  • Adult
  • Biopsy, Fine-Needle
  • Endometriosis / diagnostic imaging*
  • Endometriosis / pathology
  • Female
  • Humans
  • Skin / pathology*
  • Skin Diseases / diagnostic imaging*
  • Skin Diseases / pathology
  • Ultrasonography