[Immune reactions after DMEK, DSAEK and DALK]

Klin Monbl Augenheilkd. 2013 May;230(5):494-9. doi: 10.1055/s-0032-1328257. Epub 2013 Feb 27.
[Article in German]


Purpose: The aim of this study is to describe incidence, diagnosis and therapy for endothelial immune reactions after modern lamellar corneal transplantat surgery (DMEK, DSAEK, DALK).

Methods: A PubMed-based literature review and our own clinical and experimental data are evaluated.

Results: There is no longer an endothelial immune reaction after DALK for keratoconus. DMEK significantly reduces the risk for endothelial immune reactions after surgery for Fuchs dystrophy.

Conclusions: Modern lamellar corneal transplant techniques such as DALK and DMEK have nearly abolished the risk for endothelial immune reactions in the avascular recipient bed.

Publication types

  • English Abstract
  • Meta-Analysis
  • Review

MeSH terms

  • Comorbidity
  • Corneal Diseases / epidemiology
  • Corneal Diseases / immunology*
  • Corneal Diseases / surgery*
  • Descemet Stripping Endothelial Keratoplasty / statistics & numerical data*
  • Graft Rejection / epidemiology
  • Graft Rejection / immunology*
  • Humans
  • Immune System Diseases / epidemiology
  • Immune System Diseases / immunology*
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / immunology*
  • Prevalence
  • Risk Factors