Consumption of polyphenol plants may slow aging and associated diseases

Curr Pharm Des. 2013;19(34):6094-111. doi: 10.2174/1381612811319340004.


Slowing aging is a widely shared goal. Plant-derived polyphenols, which are found in commonly consumed food plants such as tea, cocoa, blueberry and grape, have been proposed to have many health benefits, including slowing aging. In-vivo studies have demonstrated the lifespan-extending ability of six polyphenol-containing plants. These include five widely consumed foods (tea, blueberry, cocoa, apple, pomegranate) and a flower commonly used as a folk medicine (betony). These and multiple other plant polyphenols have been shown to have beneficial effects on aging-associated changes across a variety of organisms from worm and fly to rodent and human.

Publication types

  • Review

MeSH terms

  • Aging / drug effects*
  • Aging / pathology
  • Animals
  • Bone Density / drug effects
  • Cardiovascular Diseases / drug therapy
  • Cognition Disorders / drug therapy
  • Disease Models, Animal*
  • Humans
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use*
  • Plants, Edible / chemistry*
  • Polyphenols / isolation & purification
  • Polyphenols / pharmacology
  • Polyphenols / therapeutic use*


  • Plant Extracts
  • Polyphenols