Effectiveness of influenza vaccine for preventing laboratory-confirmed influenza hospitalizations in adults, 2011-2012 influenza season

Clin Infect Dis. 2013 Jun;56(12):1774-7. doi: 10.1093/cid/cit124. Epub 2013 Feb 28.

Abstract

During the 2011-2012 influenza season, we enrolled hospitalized adults with acute respiratory illness and tested each for influenza using reverse transcription polymerase chain reaction. Influenza vaccination was verified in 35% (6/17) of adults with influenza-associated hospitalizations compared to 64% (97/152) of test-negative controls; adjusted vaccine effectiveness was 71.4% (95% confidence interval, 17.1%-94.9%).

Keywords: effectiveness; influenza vaccine; older adults.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Case-Control Studies
  • Female
  • Hospitalization / statistics & numerical data
  • Humans
  • Influenza Vaccines / administration & dosage*
  • Influenza, Human / prevention & control*
  • Male
  • Middle Aged
  • Respiratory Tract Infections / prevention & control
  • Respiratory Tract Infections / virology
  • Vaccination / statistics & numerical data

Substances

  • Influenza Vaccines