Palladium-catalyzed decarboxylative C2-acylation of indoles with α-oxocarboxylic acids

Changduo Pan; Hongming Jin; Xu Liu; Yixiang Cheng; Chengjian Zhu

doi:10.1039/c3cc40709h

Palladium-catalyzed decarboxylative C2-acylation of indoles with α-oxocarboxylic acids

Chem Commun (Camb). 2013 Apr 11;49(28):2933-5. doi: 10.1039/c3cc40709h.

Authors

Changduo Pan¹, Hongming Jin, Xu Liu, Yixiang Cheng, Chengjian Zhu

Affiliation

¹ State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China.

PMID: 23450142
DOI: 10.1039/c3cc40709h

Abstract

A palladium-catalyzed decarboxylative C2-acylation of indoles with α-oxocarboxylic acids was achieved. This protocol represents a novel and complementary approach to 2-aroylindoles.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acylation
Carboxylic Acids / chemistry*
Catalysis
Indoles / chemistry*
Palladium / chemistry*

Substances

Carboxylic Acids
Indoles
Palladium