Endothelial fatty acid transport: role of vascular endothelial growth factor B

Physiology (Bethesda). 2013 Mar;28(2):125-34. doi: 10.1152/physiol.00042.2012.


Dietary lipids present in the circulation have to be transported through the vascular endothelium to be utilized by tissue cells, a vital mechanism that is still poorly understood. Vascular endothelial growth factor B (VEGF-B) regulates this process by controlling the expression of endothelial fatty acid transporter proteins (FATPs). Here, we summarize research on the role of the vascular endothelium in nutrient transport, with emphasis on VEGF-B signaling.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport
  • Endothelium, Vascular / metabolism*
  • Fatty Acid Transport Proteins / metabolism*
  • Fatty Acids / metabolism*
  • Food
  • Humans
  • Signal Transduction
  • Vascular Endothelial Growth Factor B / metabolism*


  • Fatty Acid Transport Proteins
  • Fatty Acids
  • Vascular Endothelial Growth Factor B