Change in ocular refraction after tropicamide cycloplegia in preschool children

Klin Oczna. 2012;114(4):278-81.


Purpose: The aim of the study was to evaluate changes in ocular refraction after 1% tropicamide and its efficacy in diagnosing refractive errors in preschool children.

Material and methods: 116 children (232 eyes) at the age of 5 to 6 years participated in the study. An objective examination of refraction using autorefractor before and after 1% tropicamide cycloplegia (2 x 1 drop of the agent instilled 5 min apart) was performed in the study.

Results: After the instillation of tropicamide, the spherical component of the refractive error significantly increased by +0.78 D, while the cylindrical component (i.e. its power and axis) remained unaltered. In examining the refractive error, the mean value of the spherical component in children at the age of 5 to 6 years amounted to +1.55 D, in the cylindrical component mean value was -0.51 D, and the axis was 102 degrees.

Conclusions: 1% Tropicamide appears an effective cycloplegic agent in preschool children, excluding children with high hyperopia, anisometropia, or strabismus.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Accommodation, Ocular / drug effects*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Mydriatics / administration & dosage*
  • Mydriatics / pharmacology*
  • Refraction, Ocular / drug effects*
  • Refractive Errors / diagnosis*
  • Reproducibility of Results
  • Tropicamide / pharmacology*
  • Visual Acuity / drug effects


  • Mydriatics
  • Tropicamide