A pharmacist-led, American Heart Association Heart360 Web-enabled home blood pressure monitoring program

Circ Cardiovasc Qual Outcomes. 2013 Mar 1;6(2):157-63. doi: 10.1161/CIRCOUTCOMES.112.968172. Epub 2013 Mar 5.


Background: To determine whether a pharmacist-led, Heart360-enabled, home blood pressure monitoring (HBPM) intervention improves blood pressure (BP) control compared with usual care (UC).

Methods and results: This randomized, controlled trial was conducted in 10 Kaiser Permanente Colorado clinics. Overall, 348 patients with BP above recommended levels were randomized to the HBPM (n=175) or UC (n=173) groups. There were no statistically significant differences in baseline characteristics between the groups; however, there was a trend toward a higher baseline BP for the HBPM group compared with the UC group (148.8 versus 145.5 mm Hg for systolic BP; 89.6 versus 88.0 mm Hg for diastolic BP). At 6 months, the proportion of patients achieving BP goal was significantly higher in the HBPM group (54.1%) than in the UC group (35.4%; P<0.001). Compared with the UC group, the HBPM group experienced a -12.4-mm Hg larger (95% confidence interval, -16.3 to -8.6) reduction in systolic BP and a -5.7-mm Hg larger (95% confidence interval, -7.8 to -3.6) reduction in diastolic BP. The impact of the intervention on BP reduction was even larger for the subgroup of patients with diabetes mellitus or chronic kidney disease. The HBPM group had more e-mail and telephone contacts and greater medication regimen intensification. The proportion of patients reporting high satisfaction with hypertension care was significantly greater in the HBPM group (58%) than in the UC group (42%), P<0.001.

Conclusions: A pharmacist-led, Heart360-supported, home BP monitoring intervention led to greater BP reductions, superior BP control, and higher patient satisfaction than UC.

Trial registration: ClinicalTrials.gov NCT01162759.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • American Heart Association*
  • Antihypertensive Agents / therapeutic use
  • Blood Pressure Monitoring, Ambulatory / methods*
  • Blood Pressure* / drug effects
  • Chi-Square Distribution
  • Community Pharmacy Services*
  • Comorbidity
  • Diabetes Mellitus / epidemiology
  • Diagnosis, Computer-Assisted*
  • Female
  • Health Maintenance Organizations
  • Humans
  • Hypertension / diagnosis*
  • Hypertension / drug therapy
  • Hypertension / epidemiology
  • Hypertension / physiopathology
  • Internet*
  • Male
  • Middle Aged
  • Patient Satisfaction
  • Pharmacists*
  • Predictive Value of Tests
  • Prognosis
  • Renal Insufficiency, Chronic / epidemiology
  • Risk Factors
  • Time Factors
  • United States / epidemiology


  • Antihypertensive Agents

Associated data

  • ClinicalTrials.gov/NCT01162759