May-Thurner syndrome: diagnosis and management

Vasa. 2013 Mar;42(2):96-105. doi: 10.1024/0301-1526/a000252.


For over fifty years, the pathogenesis of May-Thurner syndrome (MTS) has been associated with chronic left common iliac vein compression resulting in the formation of intraluminal, permanent obstructive lesions. However, despite this association, the mechanism by which compression produces these lesions is unknown. Diagnostic accuracy of MTS is critical since it often afflicts young patients requiring endovascular management. This review will focus on the historical, embryological and evolutionary description of MTS and examine its development, diagnosis, clinical management and potential diagnostic errors.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Endovascular Procedures* / instrumentation
  • History, 19th Century
  • History, 20th Century
  • History, 21st Century
  • Humans
  • May-Thurner Syndrome / diagnosis*
  • May-Thurner Syndrome / embryology
  • May-Thurner Syndrome / history
  • May-Thurner Syndrome / therapy*
  • Predictive Value of Tests
  • Risk Factors
  • Treatment Outcome
  • Vascular Surgical Procedures* / instrumentation
  • Vena Cava Filters