Interplay between experimental dental pellicles and stannous-containing toothpaste on dental erosion-abrasion

Caries Res. 2013;47(4):325-9. doi: 10.1159/000347051. Epub 2013 Mar 7.

Abstract

The interaction between stannous-containing dentifrice slurry and experimentally formed pellicles was investigated on enamel and root dentin using an erosion-remineralization-abrasion cycling model. The remineralizing solutions contained no proteins (negative control), mucin, casein, mucin + casein or albumin, for experimental pellicle formation. Toothbrushing was performed with fluoride toothpaste, with (TP + Sn) and without (TP) 3,500 ppm Sn. TP + Sn reduced surface loss for both enamel and root dentin (p < 0.05). The association between TP + Sn and albumin resulted in a significantly lower enamel surface loss (p < 0.05), suggesting positive interaction of stannous ion and albumin on dental erosion-abrasion protection. A similar trend was observed for root dentin, although less pronounced.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analysis of Variance
  • Animals
  • Caseins / pharmacology
  • Dental Enamel
  • Dental Pellicle* / chemistry
  • Dental Pellicle* / physiology
  • Dentin
  • Humans
  • Milk / chemistry
  • Mucins / pharmacology
  • Salivary Proteins and Peptides / chemistry
  • Salivary Proteins and Peptides / physiology
  • Serum Albumin, Bovine / pharmacology*
  • Sodium Fluoride / therapeutic use
  • Tin Compounds / therapeutic use*
  • Tooth Abrasion / prevention & control
  • Tooth Erosion / prevention & control*
  • Tooth Remineralization*
  • Tooth Root
  • Toothpastes / chemistry
  • Toothpastes / therapeutic use*

Substances

  • Caseins
  • Mucins
  • Salivary Proteins and Peptides
  • Tin Compounds
  • Toothpastes
  • stannous chloride
  • Serum Albumin, Bovine
  • Sodium Fluoride