Synthesis of pyridine-based 1,3,4-oxadiazole derivative as fluorescence turn-on sensor for high selectivity of Ag+

J Fluoresc. 2013 Jul;23(4):785-91. doi: 10.1007/s10895-013-1213-y. Epub 2013 Mar 16.

Abstract

An oxadiazole derivative(OXD) containing symmetrical pyridine-2-formamidophenyl-binded moiety was synthesised as fluorescence turn-on sensor OA1. Its ultraviolet-visible(UV-vis) and fluorescent spectra(FS) gave prominent fluorescence enhancement only for monovalent silver ion(Ag(+)) in HEPES buffer solution (10 mM, pH = 7.0, DMF-H2O, 9:1, v/v), which indicated the photo-induced electron transfer(PET) occurred from the donor of pyridine-2-formamidophenyl group to oxadiazole fluorophore. The present study demonstrated that OA1 was a viable candidate as fluorescent receptor for a new Ag(+) sensor. And the results of fluorescent spectral titration showed this sensor formed 1:1 complex with Ag(+).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chemistry Techniques, Analytical / instrumentation*
  • Chemistry Techniques, Synthetic
  • Fluorescent Dyes / chemical synthesis*
  • Fluorescent Dyes / chemistry*
  • Optical Phenomena
  • Oxadiazoles / chemical synthesis*
  • Oxadiazoles / chemistry*
  • Pyridines / chemistry*
  • Silver / analysis*
  • Silver / chemistry
  • Spectrometry, Fluorescence

Substances

  • Fluorescent Dyes
  • Oxadiazoles
  • Pyridines
  • 1,3,4-oxadiazole
  • Silver
  • pyridine