Shock wave treatment improves nerve regeneration in the rat

Muscle Nerve. 2013 May;47(5):702-10. doi: 10.1002/mus.23631. Epub 2013 Mar 16.

Abstract

Introduction: The aims of the experiments were to: (1) determine whether low-energy shock wave treatment accelerates the recovery of muscle sensitivity and functionality after a nerve lesion; and (2) assess the effect of shock waves on the regeneration of injured nerve fibers.

Methods: After compression of a muscle nerve in rats the effects of shock wave treatment on the sequelae of the lesion were tested. In non-anesthetized animals, pressure pain thresholds and exploratory activity were determined. The influence of the treatment on the distance of nerve regeneration was studied in immunohistochemical experiments.

Results: Both behavioral and immunohistochemical data show that shock wave treatment accelerates the recovery of muscle sensitivity and functionality and promotes regeneration of injured nerve fibers.

Conclusion: Treatment with focused shock waves induces an improvement of nerve regeneration in a rodent model of nerve compression.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Action Potentials / physiology
  • Animals
  • Disease Models, Animal
  • Male
  • Nerve Crush
  • Nerve Regeneration / physiology*
  • Rats
  • Rats, Sprague-Dawley
  • Sound*
  • Sural Nerve / injuries*
  • Sural Nerve / physiopathology