Our early experience with iliofemoral vein stenting in patients with post-thrombotic syndrome

Phlebology. 2014 Jun;29(5):298-303. doi: 10.1177/0268355513477641. Epub 2013 May 3.


Introduction: Venous balloon dilation and stent therapy have been proposed as effective treatments for chronic iliofemoral thrombosis. In this study, we report our experience and describe the one-year outcome and efficacy of balloon angioplasty and stenting for the treatment of post-thrombotic syndrome (PTS) in iliofemoral vein segments.

Methods: From June 2011 to June 2012, 52 consecutive patients with chronic PTS (59 limbs; 75% women; median age 58 years; range: 23-76 years) referred to our unit for interventional assessment were included in the study. Treatment effects were assessed using Villalta scale, Venous Clinical Severity Score (VCSS) and Chronic Venous Insufficiency Questionnaire (CIVIQ)-20 for PTS, CEAP (clinical, aetiological, anatomical and pathological elements) grading and measurement of leg circumference, before and after intervention.

Results: Stenting was successfully accomplished in all patients. Coagulation abnormality was identified in 21 subjects (40.3%). CEAP grades were as follows: C3 in 19 patients, C4 in 24 patients, C5 in one patient and C6 in eight patients. According to Villalta scores, three patients were mild, seven patients were moderate and 42 patients were severe PTS. VCSS, Villalta scale and CIVIQ-20 showed a significant decrease in the severity of PTS signs and symptoms (P < 0.001). The calf and middle thigh circumferences decreased significantly on both sides (P < 0.001).

Conclusion: Treatment of iliac venous obstruction with balloon angioplasty and stenting appears to be a minimally invasive and safe therapeutic approach in patients with PTS offering quick symptomatic relief, good patency and minimal morbidity.

Keywords: Endovascular treatment; post-thrombotic syndrome; quality-of-life assessment.

MeSH terms

  • Adult
  • Aged
  • Angioplasty, Balloon / adverse effects
  • Angioplasty, Balloon / instrumentation*
  • Anticoagulants / therapeutic use
  • Chronic Disease
  • Female
  • Femoral Vein* / physiopathology
  • Humans
  • Iliac Vein* / physiopathology
  • Male
  • Middle Aged
  • Postthrombotic Syndrome / diagnosis
  • Postthrombotic Syndrome / physiopathology
  • Postthrombotic Syndrome / therapy*
  • Quality of Life
  • Severity of Illness Index
  • Stents*
  • Time Factors
  • Treatment Outcome
  • Vascular Patency
  • Young Adult


  • Anticoagulants