Tissue distribution of dextromoramide in the rat

Fundam Clin Pharmacol. 1990;4(2):163-7. doi: 10.1111/j.1472-8206.1990.tb00484.x.

Abstract

The tissue distribution of dextromoramide was studied in rats after the intraperitoneal injection of 0.2 mg/kg of the drug. The pattern of distribution was similar at 15, 30, 60 and 90 min, with the highest concentrations being found in the liver and the myocardium, while other organs were not able to concentrate dextromoramide.

MeSH terms

  • Animals
  • Chromatography, Gas
  • Dextromoramide / pharmacokinetics*
  • Injections, Intraperitoneal
  • Male
  • Rats
  • Rats, Inbred Strains
  • Tissue Distribution

Substances

  • Dextromoramide