[Lung mycosis in non neuropenic patients]

J Mycol Med. 2012 Sep;22(3):217-20. doi: 10.1016/j.mycmed.2012.05.002. Epub 2012 Jul 19.
[Article in French]

Abstract

Lung mycosis is rare. Diagnosis and treatment must be done the earliest possible.

Methods: It is about a retrospective study on clinical records including patients hospitalized for lung infection.

Results: From 2008 to 2011, 16 patients (13 men and three women, average age 42 years) developed a pulmonary infection. Twelve of our patients had respiratory or extrarespiratory histories. None of our patients had a neutropenia. The diagnoses were lung aspergilloma in four cases, invasive lung aspergillosis in three cases, allergic bronchopulmonary aspergillosis in three cases, mucormycosis in three cases, trichosporonosis in a case, actinomycosis in one case and penicilliosis in one case. An antifungal treatment consisting in amphotericin B or itraconazole was given to four patients and six patients, respectively. Surgery was chosen for six patients. The evolution was good for 12 patients, one presented renal failure, and three patients died.

MeSH terms

  • Adult
  • Aged
  • Antifungal Agents / therapeutic use
  • Combined Modality Therapy
  • Comorbidity
  • Disease Susceptibility
  • Female
  • Humans
  • Immunocompromised Host
  • Inpatients / statistics & numerical data
  • Leukocyte Count
  • Lung Diseases, Fungal / diagnostic imaging
  • Lung Diseases, Fungal / drug therapy
  • Lung Diseases, Fungal / epidemiology*
  • Lung Diseases, Fungal / immunology
  • Lung Diseases, Fungal / surgery
  • Male
  • Middle Aged
  • Neutrophils
  • Radiography
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult

Substances

  • Antifungal Agents