Assessment of the relationship between aortic pulse wave velocity and aortic arch calcification

Turk Kardiyol Dern Ars. 2012 Dec;40(8):683-9. doi: 10.5543/tkda.2012.83707.

Abstract

Objectives: We aimed to assess arterial stiffness parameters and to investigate the relationship between these parameters and aortic calcification in patients with aortic arch calcification and without symptomatic atherosclerotic disease.

Study design: The population of this study consisted of 41 patients with aortic arch calcification verified by chest X-ray (group I, 17 males, mean age 70±5 years) and individuals without aortic arch calcification (group II, 17 males, mean age 68±6 years). Subjects with symptomatic or known vascular disease were excluded from the study. The arterial stiffness parameters of all subjects were measured non-invasively with a SphygmoCor device. Aortic pulse wave velocity (PWV), augmentation pressure (AP), augmentation index (AIx) and heart rate normalized augmentation index (AIx@75) were used as parameters of arterial stiffness.

Results: The two groups were compared according to demographic characteristics, medications currently being taken, and levels of serum lipids. There was no significant difference between the groups. AP in group I was significantly higher than that of group II (p=0.002). AIx and AIx@75 were similar in both groups. Aortic PWV of group I was significantly higher than that of group II (p<0.0001).

Conclusion: According to the results of this study, the presence of aortic calcification, verified by chest radiography, was associated with increased aortic PWV.

MeSH terms

  • Aged
  • Aorta, Thoracic / pathology*
  • Aortic Diseases / diagnostic imaging
  • Aortic Diseases / pathology
  • Aortic Diseases / physiopathology*
  • Blood Pressure
  • Case-Control Studies
  • Cross-Sectional Studies
  • Female
  • Humans
  • Logistic Models
  • Male
  • Pulse Wave Analysis*
  • Radiography
  • Risk Factors
  • Vascular Calcification / diagnostic imaging
  • Vascular Calcification / pathology
  • Vascular Calcification / physiopathology*