Vitamin D and obesity

Nutrients. 2013 Mar 20;5(3):949-56. doi: 10.3390/nu5030949.


Obesity is a significant health problem world-wide, particularly in developed nations. Vitamin D deficiency is pandemic, and has been implicated in a wide variety of disease states. This paper seeks to examine the consistently reported relationship between obesity and low vitamin D concentrations, with reference to the possible underlying mechanisms. The possibility that vitamin D may assist in preventing or treating obesity is also examined, and recommendations for future research are made. There is a clear need for adequately-powered, prospective interventions which include baseline measurement of 25D concentrations and involve adequate doses of supplemental vitamin D. Until such studies have been reported, the role of vitamin D supplementation in obesity prevention remains uncertain.

Publication types

  • Review

MeSH terms

  • Calcium / metabolism
  • Humans
  • Obesity / etiology*
  • Obesity / prevention & control
  • Vitamin D / pharmacology*
  • Vitamin D Deficiency / complications*


  • Vitamin D
  • Calcium