The ami locus of the gram-positive bacterium Streptococcus pneumoniae is similar to binding protein-dependent transport operons of gram-negative bacteria

Mol Microbiol. 1990 Apr;4(4):633-44. doi: 10.1111/j.1365-2958.1990.tb00632.x.

Abstract

The complete nucleotide sequence of the ami locus of Streptococcus pneumoniae revealed the presence of six open reading frames, amiABCDEF. The predicted Ami proteins are probably involved in a transport system. The AmiA, C, D, E, and F proteins exhibit homology with components of the oligopeptide permeases (opp) of Salmonella typhimurium and Escherichia coli. Intriguingly, the AmiB protein is homologous to ArsC, a cytosolic modifier subunit of the anion pump encoded by the arsenical resistance operon of the R-factor R773 from E. coli. Data are presented which indicate that Ami is indeed a transport system.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Biological Transport
  • Carrier Proteins / genetics*
  • Molecular Sequence Data
  • Oligopeptides / metabolism
  • Operon*
  • Restriction Mapping
  • Sequence Homology, Nucleic Acid
  • Streptococcus pneumoniae / genetics*
  • Streptococcus pneumoniae / growth & development

Substances

  • Carrier Proteins
  • Oligopeptides

Associated data

  • GENBANK/X17337