Dehydrogenative alkenylation of uracils via palladium-catalyzed regioselective C-H activation

Yi-Yun Yu; Gunda I Georg

doi:10.1039/c3cc41130c

Dehydrogenative alkenylation of uracils via palladium-catalyzed regioselective C-H activation

Chem Commun (Camb). 2013 May 7;49(35):3694-6. doi: 10.1039/c3cc41130c. Epub 2013 Mar 25.

Authors

Yi-Yun Yu¹, Gunda I Georg

Affiliation

¹ Department of Chemistry and the Institute for Therapeutics Discovery and Development, University of Minnesota, 717 Delaware Street SE, Minneapolis, Minnesota 55414, USA.

Abstract

A regioselective Pd-catalyzed cross-dehydrogenative coupling between uracils and alkenes is reported. This protocol provides easy access to a variety of 5-alkenyluracil structural motifs.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Alkenes / chemistry*
Catalysis
Hydrogen / chemistry
Molecular Structure
Palladium / chemistry*
Uracil / chemistry*

Substances

Alkenes
Uracil
Palladium
Hydrogen

Abstract

Publication types

MeSH terms

Substances

Grants and funding