The "Test Your Memory" test performs better than the MMSE in a population without known cognitive dysfunction

J Neurol Sci. 2013 May 15;328(1-2):92-7. doi: 10.1016/j.jns.2013.02.028. Epub 2013 Mar 24.


Aim: To examine the relation of performance on the self-administered Test Your Memory test (TYM) and the Mini-Mental State Examination (MMSE) with a comprehensive neuropsychological assessment in a population sample including people with modest cognitive decrements.

Methods: Eighty-six participants (aged 56-77 years), without known cognitive dysfunction, performed a neuropsychological assessment including MMSE, and were asked to fill out the TYM. The relation between both the TYM and the MMSE and a neuropsychological assessment was examined by means of correlation analyses, area under the ROC curves for discriminating between a "normal" and "modest decrements"(≥1SD below the sample mean) group, and Bland-Altman plots.

Results: Correlation with the full neuropsychological assessment was significantly stronger for the TYM than the MMSE (r=0.78 versus r=0.55; Steiger's Z=2.66, p<0.01). The TYM showed an area under the ROC-curve of 0.88 (95% CI 0.80 to 0.97) for differentiating between "normal" and "modest decrements" compared with 0.71 (0.53 to 0.90) for the MMSE. Bland-Altman plots showed limits of agreement for the TYM of -1.10 to 1.10 and for the MMSE of -1.39 to 1.38.

Conclusions: The TYM showed good correlation with a neuropsychological assessment, performed better in discriminating between variations of cognition and showed more agreement with a neuropsychological assessment than the MMSE.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Attention
  • Blood Glucose
  • Chi-Square Distribution
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / physiopathology
  • Diabetes Mellitus, Type 2 / complications
  • Executive Function
  • Fasting / blood
  • Female
  • Humans
  • Language
  • Male
  • Memory Disorders / etiology
  • Mental Processes / physiology
  • Mental Status Schedule*
  • Middle Aged
  • Neuropsychological Tests*
  • Sensitivity and Specificity


  • Blood Glucose