Successful localization of residual culprit tumor in a case of tumor-induced osteomalacia using 68Ga-DOTANOC PET/CT

Clin Nucl Med. 2013 Aug;38(8):639-40. doi: 10.1097/RLU.0b013e318279eb13.


Tumor-induced osteomalacia (TIO) is a rare disease entity characterized by clinical pictures of recurrent multiple fractures and biochemical features of phosphaturia, hypophosphatemia, and low vitamin D levels. Most often TIO is caused by benign soft tissue tumors. The main issue in management of such patients is proper tumor localization, as these tumors are small and often located at obscure sites. We describe a case of TIO where residual disease was clinically suspected after tumor resection and subsequently detected using Ga-DOTANOC PET/CT.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Male
  • Middle Aged
  • Multimodal Imaging
  • Neoplasm, Residual / complications*
  • Neoplasm, Residual / diagnosis*
  • Neoplasm, Residual / diagnostic imaging
  • Organometallic Compounds*
  • Osteomalacia / etiology*
  • Positron-Emission Tomography*
  • Tomography, X-Ray Computed*


  • 68Ga-DOTANOC
  • Organometallic Compounds