Electrical induction of vision

Neurosci Biobehav Rev. 2013 Jun;37(5):803-18. doi: 10.1016/j.neubiorev.2013.03.012. Epub 2013 Mar 25.

Abstract

We assess what monkeys see during electrical stimulation of primary visual cortex (area V1) and relate the findings to visual percepts evoked electrically from human V1. Discussed are: (1) the electrical, cytoarchitectonic, and visuo-behavioural factors that affect the ability of monkeys to detect currents in V1; (2) the methods used to ascertain what monkeys see when electrical stimulation is delivered to V1; (3) a corticofugal mechanism for the induction of visual percepts; and (4) the quantity of information transferred to V1 by electrical stimulation. Experiments are proposed that should advance our understanding of how electrical stimulation affects macaque and human V1. This work contributes to the development of a cortical visual prosthesis for the blind. We dedicate this work to the late Robert W. Doty.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Electric Stimulation*
  • Humans
  • Photic Stimulation
  • Signal Detection, Psychological
  • Vision, Ocular / physiology*
  • Visual Cortex / physiology*
  • Visual Fields / physiology
  • Visual Perception / physiology*