A multicenter study for a single, three-step laser treatment for cellulite using a 1440-nm Nd:YAG laser, a novel side-firing fiber, and a temperature-sensing cannula

Aesthet Surg J. 2013 May;33(4):576-84. doi: 10.1177/1090820X13480858. Epub 2013 Mar 27.


Background: Historically, treatments for cellulite have not been able to address all of its physiological components and require multiple sessions.

Objective: The authors evaluate the safety and efficacy of a single, subdermal procedure to treat the underlying structure of cellulite.

Methods: Fifty-seven patients underwent a 3-step cellulite treatment with a 1440-nm Nd:YAG laser with a side-firing fiber and temperature-sensing cannula. Efficacy was measured by the ability of blinded evaluators to distinguish baseline photos from those taken at 3 and 6 months posttreatment, as well as their rating of the results on a 5-point, 2-category ordinal photonumeric scale when comparing baseline photos to those taken at 2, 3, and 6 months posttreatment. Patient and physician satisfaction was assessed based on completion of a satisfaction survey at 2, 3, and 6 months posttreatment. Adverse events (AE) were recorded throughout the study.

Results: At 6 months posttreatment, blinded evaluators rated at least a 1-point improvement in the appearance of cellulite in 96% of treated sites. Blinded evaluators were also able to correctly identify baseline versus posttreatment photos in 95% of cases. At least 90% of patients and physicians reported satisfaction with the results of treatment throughout 6 months. AE were mild in intensity and transient to treatment.

Conclusions: A single, 3-step, minimally invasive laser treatment using a 1440-nm Nd:YAG laser, side-firing fiber, and temperature-sensing cannula to treat the underlying structure of cellulite proved to be safe and maintained effectiveness at least 6 months posttreatment.

Level of evidence: 2.

Keywords: Nd: YAG laser; cellulite; cellulite laser treatment; cosmetic medicine; minimally invasive treatment.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue / physiopathology
  • Adipose Tissue / radiation effects*
  • Adult
  • Buttocks / physiopathology
  • Buttocks / radiation effects
  • Female
  • Follow-Up Studies
  • Humans
  • Lasers, Solid-State / therapeutic use*
  • Low-Level Light Therapy / methods*
  • Middle Aged
  • Obesity / physiopathology
  • Obesity / radiotherapy*
  • Patient Satisfaction / statistics & numerical data
  • Prospective Studies
  • Risk Assessment
  • Subcutaneous Fat / radiation effects
  • Thermosensing
  • Thigh / physiopathology
  • Thigh / radiation effects
  • Treatment Outcome
  • Young Adult