Concurrent Molecular Alterations in Tumors With Germ Line Epidermal Growth Factor Receptor T790M Mutations

Clin Lung Cancer. 2013 Jul;14(4):452-6. doi: 10.1016/j.cllc.2013.01.005. Epub 2013 Mar 26.

Publication types

  • Case Reports
  • Research Support, N.I.H., Intramural

MeSH terms

  • Adenocarcinoma / genetics*
  • Adenocarcinoma / secondary
  • Adenocarcinoma / therapy
  • Adenocarcinoma, Bronchiolo-Alveolar / genetics*
  • Adenocarcinoma, Bronchiolo-Alveolar / secondary
  • Adenocarcinoma, Bronchiolo-Alveolar / therapy
  • Aged
  • Combined Modality Therapy
  • DNA, Neoplasm / genetics
  • ErbB Receptors / genetics*
  • Female
  • Germ-Line Mutation / genetics*
  • Humans
  • Lung Neoplasms / genetics*
  • Lung Neoplasms / pathology
  • Lung Neoplasms / therapy
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / genetics*
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / therapy
  • Neoplasm Staging
  • Pedigree
  • Polymerase Chain Reaction
  • Prognosis
  • Proto-Oncogene Proteins / genetics
  • Proto-Oncogene Proteins p21(ras)
  • ras Proteins / genetics

Substances

  • DNA, Neoplasm
  • KRAS protein, human
  • Proto-Oncogene Proteins
  • EGFR protein, human
  • ErbB Receptors
  • Proto-Oncogene Proteins p21(ras)
  • ras Proteins