Osteoporosis diagnosis and medical treatment

Orthop Clin North Am. 2013 Apr;44(2):125-35. doi: 10.1016/j.ocl.2013.01.005. Epub 2013 Feb 26.

Abstract

Osteoporosis, the presence of either low bone mineral density or a history of a fragility fracture, is known to be associated with an increased risk of future fracture. Fracture prevention is possible through use of both nonpharmacologic and prescription treatments. Despite recent controversy regarding the safety of calcium supplementation and the appropriate dosing of calcium and vitamin D, calcium and vitamin D remain an important part of bone health. However, prescription osteoporosis treatments should be considered for those at higher risk for fracture, and there are currently several treatment options available.

Publication types

  • Review

MeSH terms

  • Antibodies, Monoclonal, Humanized / therapeutic use
  • Calcium / therapeutic use
  • Denosumab
  • Diphosphonates / therapeutic use
  • Hip Fractures / epidemiology
  • Hip Fractures / prevention & control
  • Humans
  • Osteoporosis / diagnosis*
  • Osteoporosis / drug therapy*
  • Osteoporosis / etiology
  • Osteoporosis / prevention & control
  • Osteoporotic Fractures / epidemiology
  • RANK Ligand / antagonists & inhibitors
  • Recurrence
  • Risk Assessment
  • Teriparatide / administration & dosage
  • Vitamin D / therapeutic use

Substances

  • Antibodies, Monoclonal, Humanized
  • Diphosphonates
  • RANK Ligand
  • Teriparatide
  • Vitamin D
  • Denosumab
  • Calcium