Micro-/nanometer rough structure of a superhydrophobic biodegradable coating by electrospraying for initial anti-bioadhesion

Adv Healthc Mater. 2013 Oct;2(10):1314-21. doi: 10.1002/adhm.201300021. Epub 2013 Apr 2.

Abstract

A novel superhydrophobic biodegradable coating with micro-/nanometer rough structure, fabricated by co-electrospraying poly(L-lactide) (PLLA) and modified silica nanoparticles (MSNs), exhibits good anti-adhesion behavior towards bacteria and cells in the initial culturing phase, which makes it a promising technology for preparing medical device coatings.

Keywords: anti-adhesion; biodegradation; electrospraying; nanoparticles; superhydrophobic surfaces.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bacterial Adhesion / drug effects
  • Biocompatible Materials / chemistry*
  • Biocompatible Materials / metabolism
  • Cell Adhesion / drug effects
  • Cell Line
  • Hydrophobic and Hydrophilic Interactions
  • Mice
  • Nanoparticles / chemistry*
  • Nanoparticles / toxicity
  • Particle Size
  • Polyesters / chemistry
  • Silicon Dioxide / chemistry
  • Staphylococcus aureus / physiology

Substances

  • Biocompatible Materials
  • Polyesters
  • poly(lactide)
  • Silicon Dioxide