[Morphogenetic variants in parents of children with recessive malformation syndromes]

Kinderarztl Prax. 1990 Mar;58(3):125-9.
[Article in German]


Informative morphogenetic variants (minor congenital anomalies) were investigated and anthropometric measurements were carried out in 17 apparently healthy mothers and fathers (parents) of 10 children with various, presumably autosomal recessive, multiple malformation syndromes. In 4 of them mild but characteristic features of the syndrome of their affected offspring could be identified. This was particularly conspicuous in the mother of a child with Dubowitz syndrome. A more thorough examination of the parents and siblings is urged for the sake of correct determination of inheritance.

Publication types

  • English Abstract

MeSH terms

  • Abnormalities, Multiple / genetics*
  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Female
  • Genes, Recessive*
  • Genetic Counseling*
  • Genetic Variation / genetics*
  • Humans
  • Infant
  • Male
  • Syndrome