Metabolic syndrome and periodontitis in Gullah African Americans with type 2 diabetes mellitus

J Clin Periodontol. 2013 Jun;40(6):599-606. doi: 10.1111/jcpe.12104. Epub 2013 Apr 5.

Abstract

Aim: To assess associations of metabolic syndrome, and its individual components, with extent of severe periodontitis among patients with type 2 diabetes mellitus (T2DM).

Materials & methods: We performed a secondary data analysis (N = 283) using a cross-sectional study population of Gullah African Americans with T2DM. Extent of severe periodontitis was assessed as total diseased tooth-sites/person [evaluated as separate outcomes: 6+mm clinical attachment level (CAL), 5+mm periodontal probing depth (PPD)] using negative binomial regression techniques. Primary independent variables assessed in separate models included metabolic syndrome (yes/no), each metabolic syndrome component (low HDL, hypertension, high triglycerides, large waist circumference) and glycemic control (poor/good).

Results: Multivariable CAL-model results showed a significant association for metabolic syndrome status with extent of severe periodontitis (RR = 2.77, p = 0.03). The separate multivariable CAL-model including each metabolic syndrome component showed marginally increased rates among those with large waist circumference (RR = 2.33, p = 0.09) and those with HbA1c ≥ 7% (RR = 1.73, p = 0.06). Multivariable PPD-models showed marginally increased rates among those with metabolic syndrome (RR = 2.18, p = 0.06).

Conclusion: Metabolic syndrome is associated with the extent of severe periodontitis in this Gullah population with T2DM.

MeSH terms

  • Adult
  • Aged
  • Black or African American*
  • Chronic Periodontitis / complications*
  • Chronic Periodontitis / ethnology
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / ethnology
  • Female
  • Humans
  • Hypertension / complications
  • Hypertriglyceridemia / complications
  • Likelihood Functions
  • Male
  • Metabolic Syndrome / complications*
  • Metabolic Syndrome / ethnology*
  • Middle Aged
  • Obesity / complications
  • Obesity / ethnology
  • Regression Analysis
  • Risk Factors
  • United States