Outcomes and effectiveness of bilateral percutaneous transluminal renal artery stenting in patients with critical bilateral renal artery stenosis

Cardiol J. 2013;20(1):25-8. doi: 10.5603/CJ.2013.0005.

Abstract

Background: The aim of this study was to assess the effects of percutaneous bilateral renal artery stenting in patients with atherosclerotic renal artery stenosis and in-hospital and 4 month outcome of the procedure, focusing on the changes in renal function and blood pressure.

Methods: Five consecutive patients (mean age: 64.8 ± 9.7 years, 1 women) with bilateral renal artery stenoses underwent percutaneous interventions. We compared blood pressure, number of oral antihypertensive medications, and renal function changes preprocedure and postprocedure at 4 months follow-up.

Results: A total of 5 bilateral atherosclerotic renal artery stenosis patients underwent percutaneous transluminal renal angioplasty and 10 stents were placed. Although systolic and diastolic blood pressures were significantly decreased in follow-up period, glomerular filtration rates were not significantly changed as compared with baseline data (p = 0.009, p = 0.008, p = 1.00, respectively). Also, the number of oral antihypertensive medications were significantly decreased at follow-up period (p = 0.03).

Conclusions: Bilateral renal artery stenting provides a beneficial outcome such as stabilization of renal functions, significant improvement in blood pressure control and reduction in the number of oral antihypertensive medications at follow-up.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Angioplasty / methods*
  • Antihypertensive Agents / therapeutic use
  • Atherosclerosis / pathology
  • Atherosclerosis / therapy*
  • Blood Pressure
  • Female
  • Follow-Up Studies
  • Glomerular Filtration Rate
  • Humans
  • Hypertension, Renal / drug therapy
  • Hypertension, Renal / pathology
  • Hypertension, Renal / therapy*
  • Male
  • Middle Aged
  • Renal Artery / pathology
  • Renal Artery Obstruction / pathology
  • Renal Artery Obstruction / therapy*
  • Stents*
  • Treatment Outcome

Substances

  • Antihypertensive Agents