Differentiation of Bacillus anthracis, B. cereus, and B. thuringiensis on the basis of the csaB gene reflects host source

Appl Environ Microbiol. 2013 Jun;79(12):3860-3. doi: 10.1128/AEM.00591-13. Epub 2013 Apr 5.

Abstract

csaB gene analysis clustered 198 strains of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis into two groups related to mammalian and insect hosts, respectively. Mammal-related group I strains also have more S-layer homology (SLH) protein genes than group II strains. This indicates that csaB-based differentiation reflects selective pressure from animal hosts.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehyde-Ketone Transferases / genetics*
  • Bacillus anthracis / enzymology*
  • Bacillus anthracis / genetics
  • Bacillus cereus / enzymology*
  • Bacillus cereus / genetics
  • Bacillus thuringiensis / enzymology*
  • Bacillus thuringiensis / genetics
  • Base Sequence
  • Cluster Analysis
  • DNA Primers / genetics
  • Evolution, Molecular*
  • Genetic Variation / genetics*
  • Host-Pathogen Interactions
  • Molecular Sequence Data
  • Phylogeny
  • Selection, Genetic*
  • Sequence Analysis, DNA

Substances

  • DNA Primers
  • Aldehyde-Ketone Transferases
  • polysaccharide pyruvyltransferase