Severe monobacterial necrotizing soft tissue infection by group A Streptococcus: A surgical emergency

Asian Pac J Trop Biomed. 2012 Mar;2(3):250-2. doi: 10.1016/S2221-1691(12)60052-5.

Abstract

Eight percent of necrotizing soft tissue infections (NSTI) are attributable to group A Streptococci (GAS), and among these, 50% develop streptococcal toxic shock syndrome. The reported mortality associated with NSTI reaches 32%. We present cases of two healthy individuals with minor GAS skin infection which developed to a rapidly progressed NSTI and sepsis despite of the antibiotic treatment, aiming to discuss the lessons learned from the course and management of these patients.

Keywords: Fulminant skin necrosis; Group A Streptococci; Necrotizing soft tissue infection.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Arm / microbiology
  • Arm / pathology
  • Arm / surgery
  • Fasciitis, Necrotizing*
  • Foot / microbiology
  • Foot / pathology
  • Foot / surgery
  • Humans
  • Male
  • Middle Aged
  • Soft Tissue Infections*
  • Streptococcal Infections*
  • Streptococcus pyogenes*
  • Young Adult

Substances

  • Anti-Bacterial Agents