Unilocular anterior mandibular swelling

Int J Pediatr Otorhinolaryngol. 2013 Jun;77(6):964-71. doi: 10.1016/j.ijporl.2013.03.018. Epub 2013 Apr 6.


Purpose: To report a rare case of chondromyxoid fibroma, presenting as an unilocular anterior mandibular swelling, which is one of the least common tumours of bone comprising less than 1% of bone tumours and to review the differential diagnosis and literature for a better understanding of this disease as well as addressing the controversies in respect with its treatment.

Materials and methods: Previous reports about this lesion in literature were reviewed wherein data was recorded about the age, sex, race, location of pathology, presenting signs and symptoms, duration of pathology, size, radiographic findings, treatment and any recurrence on follow-up.

Results: 25 cases were studied and data compiled. Multisectional histopathological examination is advocated to differentiate it from osteosarcoma. Enucleation with or without curettage with long-term follow-up has been considered to be a satisfactory treatment modality.

Conclusion: The rarity of the lesion, limited data on the clinical presentation, histological dilemma and treatment options replete with controversies make it a tough predicament. A thorough understanding of the disease and treatment options is indispensable to treat such a case.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Biopsy, Needle
  • Child
  • Chondroma / diagnosis
  • Chondroma / pathology*
  • Chondroma / surgery
  • Diagnosis, Differential
  • Edema / diagnosis
  • Edema / etiology
  • Female
  • Fibroma / diagnosis
  • Fibroma / pathology*
  • Fibroma / surgery
  • Humans
  • Immunohistochemistry
  • Mandible / physiopathology
  • Mandibular Neoplasms / diagnosis
  • Mandibular Neoplasms / pathology*
  • Mandibular Neoplasms / surgery
  • Neoplasm Staging
  • Osteosarcoma / diagnosis
  • Osteosarcoma / pathology*
  • Osteosarcoma / surgery
  • Rare Diseases
  • Risk Assessment
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome