Effect of passive smoking on female breast cancer in China: a meta-analysis

Asia Pac J Public Health. 2015 Mar;27(2):NP58-64. doi: 10.1177/1010539513481493. Epub 2013 Apr 9.


The objective is to explore the relationship between passive smoking and female breast cancer using meta-analysis. Literature on risk factors for female breast cancer published from January 2001 to December 2011 was collected from CBM, CAJD, VIP, WanFangData, and MEDLINE databases. The meta-analysis was performed using Review Manager 5.0.24. A total of 8 studies were included according to inclusion and exclusion standards. The results of the meta-analysis indicated that the combined odds ratio (OR) estimate for those who had been exposed to passive smoke from tobacco was 1.67 (95% confidence interval [CI] = 1.27-2.21). Results of the subgroup analysis were consistent with an OR = 1.98 (95% CI = 1.63-2.42) for 1:1 paired design research and 1.60 (95% CI = 1.08-2.37) for the group design research. Results suggest a possible association between passive tobacco smoke and female breast cancer in China.

Keywords: Chinese; breast cancer; meta-analysis; tobacco smoke pollution; women’s health.

Publication types

  • Meta-Analysis

MeSH terms

  • Breast Neoplasms / chemically induced*
  • Case-Control Studies
  • China / epidemiology
  • Female
  • Humans
  • Odds Ratio
  • Risk Factors
  • Tobacco
  • Tobacco Smoke Pollution / adverse effects*


  • Tobacco Smoke Pollution