Early development in infants at risk of childhood apraxia of speech: a longitudinal investigation

Dev Neuropsychol. 2013;38(3):197-210. doi: 10.1080/87565641.2013.774405.


This study examined early features of the heritable phenotype associated with childhood apraxia-of-speech (CAS). We compared speech and language development from 9 to 24 months of age in eight children at familial risk of CAS to that of eight infants with no such family history. At-risk infants scored lower on expressive language, speech development, and fine motor skills. Results support a broad, heritable verbal trait deficit for children at risk of CAS. Single case analyses showed poor prelinguistic speech development can dissociate from emerging receptive language and conceptualization skills, consistent with a deficit originating in speech motor control.

MeSH terms

  • Apraxias / complications*
  • Apraxias / diagnosis
  • Caregivers
  • Child, Preschool
  • Concept Formation / physiology
  • Female
  • Humans
  • Infant
  • Language Development Disorders / complications*
  • Language Development Disorders / diagnosis
  • Longitudinal Studies
  • Male
  • Psychiatric Status Rating Scales
  • Psychomotor Performance
  • Risk Factors
  • Speech Production Measurement
  • Surveys and Questionnaires