Brucellosis is a rare zoonotic disease in the UK but endemic in parts of the world, including the Mediterranean region, South and Central America, Caribbean, Africa and Persian Gulf. Therefore, the most common routes of transmission to the UK are either through emigration or by vacationing in such endemic regions. This provides us the challenge even today, especially in the extensive multi-ethnic area of East London, in recognising the signs and symptoms of the rare disease of Brucellosis. Here, we report such a patient case of Brucellosis.