Randomized clinical trial of CO2 laser pinpoint irradiation technique with/without needling for ice pick acne scars

J Cosmet Laser Ther. 2013 Jun;15(3):177-82. doi: 10.3109/14764172.2013.793584. Epub 2013 May 8.


Background: Pinpoint irradiation technique accompanying by needling is an effective treatment for atrophic acne scars as fractional photothermolysis. It often induces microscopic thermal wounds to achieve skin rejuvenation treatment for ice pick acne scars.

Objective: This study was designed to prospectively evaluate the use of a pinpoint irradiation technique without needling in the treatment of ice pick acne scars.

Methods: Sixty patients with ice pick acne scars were included in this open label pilot study. Pinpoint irradiation technique by CO2 laser without and with needling applied for study and control groups, respectively.

Results: There was a statistically insignificant difference in the improvement results between the study and control groups (p > 0.05). But there were statistically significant differences in acne scar severity index and qualitative scarring grading system between before and after treatment of both groups (p < 0.05).

Conclusion: Pinpoint irradiation technique by CO2 laser without needling is safe and effective as pinpoint irradiation technique with needling. Clinical improvement was achieved in all 30 patients without adverse effects.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Acne Vulgaris / radiotherapy*
  • Adult
  • Case-Control Studies
  • Chi-Square Distribution
  • Cicatrix / radiotherapy*
  • Female
  • Humans
  • Lasers, Gas / therapeutic use*
  • Low-Level Light Therapy / methods*
  • Male
  • Needles
  • Treatment Outcome