NPMc+ and FLT3_ITD mutations cooperate in inducing acute leukaemia in a novel mouse model

Leukemia. 2013 Nov;27(11):2248-51. doi: 10.1038/leu.2013.114. Epub 2013 Apr 15.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Animals
  • Disease Models, Animal*
  • Female
  • Humans
  • Leukemia / genetics
  • Leukemia / metabolism
  • Leukemia / pathology*
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mutation / genetics*
  • Nuclear Proteins / physiology*
  • Survival Rate
  • Tandem Repeat Sequences / genetics*
  • fms-Like Tyrosine Kinase 3 / genetics*

Substances

  • Nuclear Proteins
  • nucleophosmin
  • FLT3 protein, human
  • fms-Like Tyrosine Kinase 3