Motor vehicle traffic crashes are the leading cause of unintentional injury-related death in the United States, resulting in 33,687 deaths in 2010. Pedestrian travel makes up 10.5% of all trips (i.e., any travel from one address to another) taken in the United States, and pedestrians represent 13% of all motor vehicle traffic-related deaths. To determine traffic-related pedestrian death rates by sex, age group, race/ethnicity, and urbanization level, CDC analyzed 2001-2010 data from the National Vital Statistics System (NVSS). The results of that analysis indicated that the overall, annualized, age-adjusted traffic-related pedestrian death rate was 1.58 deaths per 100,000 population. Persons aged ≥75 years and those categorized as American Indian/Alaska Native (AI/AN) had the highest death rates, and age group differences varied by race/ethnicity. The results suggest that the overall pedestrian death rate could increase with the aging and growing racial/ethnic diversity of the U.S. population. The U.S. Census Bureau projects that the number of persons aged ≥75 years will more than double, from approximately 18 million in 2011 (6% of the U.S. population) to 44 million in 2040 (12% of the population); minority racial/ethnic populations are projected to increase from 116 million in 2010 (37% of the population) to 186 million in 2040 (49% of the population).* Strategies to prevent pedestrian deaths should include consideration of the needs of older adults and cultural differences among racial/ethnic populations.