Long-term habituation of the acoustic startle response: role of the cerebellar vermis

Neuroscience. 1990;35(1):79-84. doi: 10.1016/0306-4522(90)90122-k.


The cerebellar vermis has been recognized as a key region of a circuit essential for long-term habituation of the acoustic startle response in rats. The removal of this neuronal structure before training prevents the build-up of this long-term behavioral change. Our data show that, when the same lesion is performed after training for long-term habituation, the learned behavior is not affected. These results indicate that the cerebellar vermis is essential for the acquisition, but not for the retention of long-term habituation of the startle response.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acoustic Stimulation
  • Animals
  • Cerebellum / physiology*
  • Female
  • Habituation, Psychophysiologic*
  • Rats
  • Rats, Inbred Strains
  • Reflex, Startle / physiology*