Joint hypermobility syndrome

Rheum Dis Clin North Am. 2013 May;39(2):419-30. doi: 10.1016/j.rdc.2013.03.003.


Although perceived as a rare condition, joint hypermobility syndrome is common. Its prevalence in rheumatology clinics is extremely high. Early estimates suggest that it may be the most common of all rheumatologic conditions. The problem lies in the general lack of awareness of the syndrome, its means of recognition, and the resultant failure to diagnose it correctly when present. It is a worldwide problem. This article provides an overview of hypermobility and hypermobility syndrome, stressing its multisystemic nature and the negative impact that it may have on quality of life, with particular reference to gastrointestinal involvement.

Publication types

  • Review

MeSH terms

  • Chronic Pain / pathology*
  • Chronic Pain / physiopathology
  • Ehlers-Danlos Syndrome / diagnosis*
  • Ehlers-Danlos Syndrome / physiopathology
  • Gastrointestinal Motility / physiology
  • Gastrointestinal Tract / pathology
  • Humans
  • Joint Instability / diagnosis*
  • Joint Instability / physiopathology
  • Primary Dysautonomias / pathology*
  • Primary Dysautonomias / physiopathology
  • Quality of Life
  • Surveys and Questionnaires