Bioprosthetic mitral valve endocarditis after percutaneous device closure of severe paravalvular leak

Ann Thorac Surg. 2013 May;95(5):1787-9. doi: 10.1016/j.athoracsur.2012.10.051.


A large mitral paravalvular leak in a 63-year-old patient was closed by percutaneous placement of 2 Amplatzer Septal Occluder (AGA Medical Corporation, Plymouth, MN) devices. The patient had a residual paravalvular leak and subsequently developed infective endocarditis that was successfully treated by removal of all hardware and implantation of a new valve. Transcatheter treatment of paravalvular leaks may be useful in select patients who are poor candidates for open surgery; however, one must be aware of the potential complications. This report underscores the risk of device infection that may be increased if there is turbulence related to residual paravalvular leaks.

Publication types

  • Case Reports

MeSH terms

  • Bioprosthesis / adverse effects*
  • Endocarditis / etiology*
  • Heart Valve Prosthesis Implantation / adverse effects*
  • Humans
  • Male
  • Middle Aged
  • Mitral Valve / surgery*
  • Septal Occluder Device / adverse effects*