Phytoestrogenic potential of Cyclopia extracts and polyphenols

Planta Med. 2013 May;79(7):580-90. doi: 10.1055/s-0032-1328463. Epub 2013 Apr 22.


Cyclopia Vent. species, commonly known as honeybush, are endemic to Southern Africa. The plant is traditionally used as an herbal tea but several health benefits have recently been recorded. This minireview presents an overview of polyphenols found in Cyclopia and focuses on the phytoestrogenic potential of selected polyphenols and of extracts prepared from the plant.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cyclopia Plant / chemistry*
  • Female
  • Humans
  • Phytoestrogens / pharmacology
  • Phytoestrogens / therapeutic use*
  • Phytotherapy*
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use*
  • Polyphenols / pharmacology
  • Polyphenols / therapeutic use*
  • South Africa


  • Phytoestrogens
  • Plant Extracts
  • Polyphenols