Reconstruction of three dimensional structures from electron micrographs

Nature. 1968 Jan 13;217(5124):130-4. doi: 10.1038/217130a0.


General principles are formulated for the objective reconstruction of a three dimensional object from a set of electron microscope images. These principles are applied to the calculation of a three dimensional density map of the tail of bacteriophage T4.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteriophage T4 / ultrastructure
  • Image Processing, Computer-Assisted
  • Imaging, Three-Dimensional / methods*
  • Microscopy, Electron / methods*