Abstract
The selective synthesis of tetrahydroquinolines and fluorinated arylamines was performed in superacid HF/SbF5 through a superelectrophilic ammonium-carbenium activation process. This anti-Markovnikov oriented reaction was applied to the straightforward synthesis of highly valued (fluorinated) nitrogen-containing heterocyclic compounds.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Antimony / chemistry*
-
Cyclization
-
Drug Design*
-
Fluorides / chemistry*
-
Hydrocarbons, Fluorinated / chemical synthesis*
-
Hydrocarbons, Fluorinated / chemistry
-
Hydrofluoric Acid / chemistry*
-
Magnetic Resonance Spectroscopy
-
Mass Spectrometry
-
Molecular Structure
-
Polycyclic Compounds / chemical synthesis*
-
Polycyclic Compounds / chemistry
-
Quinolines / chemical synthesis*
-
Quinolines / chemistry
Substances
-
Hydrocarbons, Fluorinated
-
Polycyclic Compounds
-
Quinolines
-
antimony pentafluoride
-
Antimony
-
1,2,3,4-tetrahydroquinoline
-
Fluorides
-
Hydrofluoric Acid