A congested in,in-diphosphine

Org Lett. 2013 May 3;15(9):2179-81. doi: 10.1021/ol400728m. Epub 2013 Apr 23.

Abstract

The synthesis and characterization of the bis(triarylphosphine) 3 are described. Slow protonation of an inwardly directed phosphine is possible, but the phosphines do not react with larger reagents. X-ray structures of the parent compound, its HCl salt, and the corresponding trisulfone are reported. Compound 3 was resolved by chiral chromatography, but the barrier to racemization is only 20.7 kcal/mol.