Individual music therapy for agitation in dementia: an exploratory randomized controlled trial

Aging Ment Health. 2013;17(6):667-78. doi: 10.1080/13607863.2013.790926. Epub 2013 Apr 27.


Objectives: Agitation in nursing home residents with dementia leads to increase in psychotropic medication, decrease in quality of life, and to patient distress and caregiver burden. Music therapy has previously been found effective in treatment of agitation in dementia care but studies have been methodologically insufficient. The aim of this study was to examine the effect of individual music therapy on agitation in persons with moderate/severe dementia living in nursing homes, and to explore its effect on psychotropic medication and quality of life.

Method: In a crossover trial, 42 participants with dementia were randomized to a sequence of six weeks of individual music therapy and six weeks of standard care. Outcome measures included agitation, quality of life and medication.

Results: Agitation disruptiveness increased during standard care and decreased during music therapy. The difference at -6.77 (95% CI (confidence interval): -12.71, -0.83) was significant (p = 0.027), with a medium effect size (0.50). The prescription of psychotropic medication increased significantly more often during standard care than during music therapy (p = 0.02).

Conclusion: This study shows that six weeks of music therapy reduces agitation disruptiveness and prevents medication increases in people with dementia. The positive trends in relation to agitation frequency and quality of life call for further research with a larger sample.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cross-Over Studies
  • Dementia / drug therapy
  • Dementia / psychology
  • Dementia / therapy*
  • Female
  • Humans
  • Male
  • Music Therapy / methods*
  • Nursing Homes
  • Psychiatric Status Rating Scales
  • Psychomotor Agitation / therapy*
  • Psychotropic Drugs / administration & dosage*
  • Quality of Life
  • Treatment Outcome


  • Psychotropic Drugs